Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6

Stable Identifier
R-HSA-9020249
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6
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An unknown hydroperoxy reductase mediates the reduction of 4(S)-hydroperoxy-17(S)-hydroxydocosahexaenoic acid (4(S)-Hp-17(S)-HDHA) to 4(S),17(S)-dihydroxydocosahexaenoic acid (AT-RvD6) (Serhan et al. 2002).

Literature References
PubMed ID Title Journal Year
12391014 Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

Serhan, CN, Hong, S, Gronert, K, Colgan, SP, Devchand, PR, Mirick, G, Moussignac, RL

J. Exp. Med. 2002
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
oxidoreductase activity of Hydroperoxy reductase [cytosol]
Physical Entity
Hydroperoxy reductase [cytosol]
Activity
oxidoreductase activity (0016491)
Authored
Jassal, B  (2017-09-05)
Reviewed
Hansen, TV  (2018-02-21)
Created
Jassal, B  (2017-09-05)
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