Reactome | RAC3 GDIs block activation of RAC3

RAC3 GDIs block activation of RAC3

Stable Identifier

R-HSA-9018807

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane, cytosol

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ARHGDIB, a GDP dissociation inhibitor (GDI), binds to RAC3 (Zhang et al. 2009) and is a candidate RAC3 inhibitor.

Literature References

PubMed ID	Title	Journal	Year
19269969	Silencing of D4-GDI inhibits growth and invasive behavior in MDA-MB-231 cells by activation of Rac-dependent p38 and JNK signaling Zhang, Y, Rivera Rosado, LA, Moon, SY, Zhang, B	J. Biol. Chem.	2009