Biosynthesis of D-series resolvins

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R-HSA-9018676
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Pathway
Species
Homo sapiens
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The D-series resolvins (RvD1-6) are biosynthesised from the precursor ω-3 fatty acid docosahexaenoic acid (DHA), either via aspirin-triggered cylcooxygenase catalysis (17(R) AT-RvDs) or via the lipoxygenase pathway (described here) forming the epimeric 17(S)-RvD1-6 resolvins (Serhan et al. 2014, Bannenberg & Serhan 2010).

Literature References
PubMed ID Title Journal Year
20708099 Specialized pro-resolving lipid mediators in the inflammatory response: An update

Serhan, CN, Bannenberg, G

Biochim. Biophys. Acta 2010
25359497 Lipid mediators in the resolution of inflammation

Serhan, CN, Levy, BD, Chiang, N, Dalli, J

Cold Spring Harb Perspect Biol 2014
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