Biosynthesis of D-series resolvins

Stable Identifier
R-HSA-9018676
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Biosynthesis of D-series resolvins
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The D-series resolvins (RvD1-6) are biosynthesised from the precursor ω-3 fatty acid docosahexaenoic acid (DHA), either via aspirin-triggered cylcooxygenase catalysis (17(R) AT-RvDs) or via the lipoxygenase pathway (described here) forming the epimeric 17(S)-RvD1-6 resolvins (Serhan et al. 2014, Bannenberg & Serhan 2010).
Literature References
PubMed ID Title Journal Year
20708099 Specialized pro-resolving lipid mediators in the inflammatory response: An update

Serhan, CN, Bannenberg, G

Biochim. Biophys. Acta 2010
25359497 Lipid mediators in the resolution of inflammation

Serhan, CN, Levy, BD, Chiang, N, Dalli, J

Cold Spring Harb Perspect Biol 2014
Participants
Events
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Event Information
Go Biological Process
long-chain fatty acid biosynthetic process (0042759)
Orthologous Events
Biosynthesis of D-series resolvins (Bos taurus)
Biosynthesis of D-series resolvins (Caenorhabditis elegans)
Biosynthesis of D-series resolvins (Canis familiaris)
Biosynthesis of D-series resolvins (Danio rerio)
Biosynthesis of D-series resolvins (Dictyostelium discoideum)
Biosynthesis of D-series resolvins (Drosophila melanogaster)
Biosynthesis of D-series resolvins (Gallus gallus)
Biosynthesis of D-series resolvins (Mus musculus)
Biosynthesis of D-series resolvins (Plasmodium falciparum)
Biosynthesis of D-series resolvins (Rattus norvegicus)
Biosynthesis of D-series resolvins (Saccharomyces cerevisiae)
Biosynthesis of D-series resolvins (Schizosaccharomyces pombe)
Biosynthesis of D-series resolvins (Sus scrofa)
Biosynthesis of D-series resolvins (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Jassal, B  (2017-09-04)
Reviewed
Hansen, TV  (2018-02-21)
Created
Jassal, B  (2017-09-04)
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