EBAG9, also known as RCAS1, is an estrogen-responsive gene with an ERE in the 5' flanking region. This element is bound by estrogen and ESR1 to stimulate transcription, as assessed by electrophoretic mobility shift and luciferase assay (Ikeda et al, 2000). EBAG9 may play a role in immune response during tumorigenesis, and expression of EBAG9 is often upregulated in malignant tumors (Jóźwicki et al, 2015; Miyazaki et al, 2014; Xu et al, 2014; Tanaka et al, 2014; Wolf et al, 2010; Maeyama et al, 2011)
Kitamura, R, Matsubara, R, Tanaka, H, Sasaguri, M, Nakamura, S, Kawano, S, Toyoshima, T, Goto, Y, Sonoda, K
Siekiera, J, Jóźwicki, W, Brożyna, AA, Slominski, AT
Rehm, A, Gerlach, K, Rüder, C, Dörken, B, Schuck, S, Otto, A, Wolf, J, Reimer, TA, Müller, EC
Tsutsumi, O, Sato, M, Inazawa, J, Emi, M, Tsuneizumi, M, Ikeda, K, Tsuchiya, F, Muramatsu, M, Inoue, S, Imoto, I
Maeyama, Y, Iimura, Y, Kubo, S, Kondo, S, Onodera, M, Sakiyama, Y, Yamano, T, Otsu, M, Ariga, T
Xu, C, Yu, LK, Zhang, X
Miyazaki, T, Kondo, T, Takahashi, S, Ikeda, K, Horie-Inoue, K, Inoue, S
© 2023 Reactome
