NOTCH1 coactivator complex binds NOTCH3 gene

Stable Identifier
R-HSA-9017835
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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NOTCH1 coactivator complex binds NOTCH3 gene
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NOTCH1 and RBPJ (CSL), likely in the form of the NOTCH1 coactivator complex, bind to the RBPJ response elements in the second intron of the NOTCH3 gene (Ohashi et al. 2010).

Literature References
PubMed ID Title Journal Year
20801121 NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network

Ohashi, S, Natsuizaka, M, Yashiro-Ohtani, Y, Kalman, RA, Nakagawa, M, Wu, L, Klein-Szanto, AJ, Herlyn, M, Diehl, JA, Katz, JP, Pear, WS, Seykora, JT, Nakagawa, H

Gastroenterology 2010
Participants
Input
Output
Participant Of
hasEvent
Event Information
Go Biological Process
positive regulation of Notch signaling pathway (0045747)
Authored
Orlic-Milacic, M  (2017-09-20)
Reviewed
Haw, R  (2017-10-30)
Created
Orlic-Milacic, M  (2017-08-28)