RHOG binds effectors at the ER membrane

Stable Identifier
R-HSA-9014467
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Active GTP-bound RHOG binds to and activates kinectin (KTN1) at the endoplasmic reticulum membrane (Vignal et al. 2001).

In addition, active RHOG binds to the following candidate endoplasmic reticulum membrane effectors identified in the high throughput screen by Bagci et al. 2020:
ANKLE2 (Bagci et al. 2020)
EMD (Bagci et al. 2020)
ESYT1 (Bagci et al. 2020)
LBR (Bagci et al. 2020)
LEMD3 (Bagci et al. 2020)
LETM1 (Bagci et al. 2020)
LMAN1 (Bagci et al. 2020)
NDUFA5 (Bagci et al. 2020)
PGRMC2 (Bagci et al. 2020)
STX5 (Bagci et al. 2020)
VAPB (Bagci et al. 2020)
VRK2 (Bagci et al. 2020)
YKT6 (Bagci et al. 2020)

Literature References
PubMed ID Title Journal Year
31871319 Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

Bagci, H, Sriskandarajah, N, Robert, A, Boulais, J, Elkholi, IE, Tran, V, Lin, ZY, Thibault, MP, Dubé, N, Faubert, D, Hipfner, DR, Gingras, AC, Cote, JF

Nat. Cell Biol. 2020
11689693 Kinectin is a key effector of RhoG microtubule-dependent cellular activity

Vignal, E, Blangy, A, Martin, M, Gauthier-Rouvière, C, Fort, P

Mol. Cell. Biol. 2001
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