GDIs block activation of RHOG

Stable Identifier
R-HSA-9014456
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The following GDP dissociation inhibitors (GDIs) bind to RHOG and inhibit its activation:
ARHGDIA (Elfenbein et al. 2009)
ARHGDIB (Vignal et al. 2001)
ARHGDIG (Zalcman et al. 1996; Brunet et al. 2002)

Literature References
PubMed ID Title Journal Year
11967128 RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain

Brunet, N, Morin, A, Olofsson, B

Traffic 2002
11689693 Kinectin is a key effector of RhoG microtubule-dependent cellular activity

Vignal, E, Blangy, A, Martin, M, Gauthier-Rouvière, C, Fort, P

Mol. Cell. Biol. 2001
19581409 Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway

Elfenbein, A, Rhodes, JM, Meller, J, Schwartz, MA, Matsuda, M, Simons, M

J. Cell Biol. 2009
8939998 RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG

Zalcman, G, Closson, V, Camonis, J, Honoré, N, Rousseau-Merck, MF, Tavitian, A, Olofsson, B

J. Biol. Chem. 1996
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