RAC2 binds effectors at the phagocytic vesicle membrane

Stable Identifier
R-HSA-9014424
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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RAC2 binds to and activates the NOX2 complex and the phagocytic vesicle membrane (Knaus et al. 1991; Kim et al. 2001; Carstanjen et al. 2005).

Literature References
PubMed ID Title Journal Year
1660188 Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

Knaus, UG, Heyworth, PG, Evans, T, Curnutte, JT, Bokoch, GM

Science 1991
11145705 Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways

Kim, C, Dinauer, MC

J. Immunol. 2001
15814684 Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways

Carstanjen, D, Yamauchi, A, Koornneef, A, Zang, H, Filippi, MD, Harris, C, Towe, J, Atkinson, S, Zheng, Y, Dinauer, MC, Williams, DA

J. Immunol. 2005
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