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SARM:TICAM1:viral dsRNA:TLR3 [endosome membrane]
Stable Identifier
R-HSA-9014322
Type
Complex
Species
Homo sapiens
Related Species
Influenza A virus,
Rotavirus,
Hepatitis B virus,
Hepatitis C Virus,
Human herpesvirus 1
Compartment
endosome membrane
Synonyms
SARM:TICAM1:activated TLR3, SARM:TRIF:viral dsRNA:TLR3
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
SARM binds viral dsRNA:TLR3:TICAM1 (Homo sapiens)
SARM:TICAM1:viral dsRNA:TLR3 [endosome membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
16964262
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
Schröder, M
,
Stack, J
,
Moynagh, PN
,
Carty, M
,
Bowie, AG
,
Goodbody, R
Nat. Immunol.
2006
Participants
components
SARM-1 [cytosol]
(Homo sapiens)
viral dsRNA:TLR3:TICAM1 [endosome membrane]
(Homo sapiens)
Participates
as an output of
SARM binds viral dsRNA:TLR3:TICAM1 (Homo sapiens)
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