HEY2 gene expression is positively regulated by NOTCH3

Stable Identifier
R-HSA-9014141
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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HEY2 gene expression is positively regulated by NOTCH3
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Based on a study involving mouse and rat proteins and DNA, NOTCH3 coactivator complex positively regulates transcription of HEY2 (HRT2). Direct binding of NOTCH3 to the HEY2 gene promoter has not been demonstrated (Wang et al. 2002).
Participants
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Output
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as an event of
Event Information
Go Biological Process
positive regulation of transcription of Notch receptor target (0007221)
This event is regulated
Positively by
Regulator
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
Inferred From
Hey2 gene expression is positively regulated by Notch3 (Mus musculus)
Authored
Orlic-Milacic, M  (2017-09-20)
Reviewed
Haw, R  (2017-10-30)
Created
Orlic-Milacic, M  (2017-07-26)
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