RHOD binds effectors at the endosome membrane

Stable Identifier
R-HSA-9013438
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Active GTP-bound RHOD binds the following effectors at the endosome membrane:
ANKFY1 (Nehru et al. 2013)
DIAPH2-3 (DIAPH2 isoform C) (Gasman et al. 2003)

The following candidate effectors that can localize to endosomal membranes were reported to bind active RHOD by Bagci et al. 2020:
EMD (Bagci et al. 2020)
LBR (Bagci et al. 2020)
LEMD3 (Bagci et al. 2020)
MOSPD2 (Bagci et al. 2020)
PGRMC2 (Bagci et al. 2020)

Literature References
PubMed ID Title Journal Year
31871319 Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

Bagci, H, Sriskandarajah, N, Robert, A, Boulais, J, Elkholi, IE, Tran, V, Lin, ZY, Thibault, MP, Dubé, N, Faubert, D, Hipfner, DR, Gingras, AC, Cote, JF

Nat. Cell Biol. 2020
24102721 RhoD binds the Rab5 effector Rabankyrin-5 and has a role in trafficking of the platelet-derived growth factor receptor

Nehru, V, Voytyuk, O, Lennartsson, J, Aspenström, P

Traffic 2013
12577064 RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase

Gasman, S, Kalaidzidis, Y, Zerial, M

Nat. Cell Biol. 2003
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