This pathway catalogues RHOD GTPase activator proteins (GAPs) and RHOD effectors. RHOD is an atypical RHO GTPase with no known guanine nucleotide exchange factors (GEFs) and no GDP dissociation inhibitors (GDIs) (Blom et al. 2017). RHOD possesses an elevated intrinsic guanine nucleotide exchange activity and auto-activates (Jaiswal, Fansa et al. 2013). RHOD regulates cytoskeletal dynamics and intracellular transport of vesicles (Gad and Aspenstrom 2010; Aspenstrom et al. 2014), especially actin-dependent movement of endosomes (Randazzo 2003).