EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K

Stable Identifier
R-HSA-9012657
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Phosphatidylinositol 4,5-bisphosphate 3-kinase (PI3K) binds phosphorylated IRS2 associated with the phosphorylated EPOR (Bouscary et al. 2003).
Literature References
PubMed ID Title Journal Year
12506011 Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation

Claessens, YE, Mayeux, P, Fontenay-Roupie, M, Bouscary, D, Pene, F, Lacombe, C, Muller, O, Chrétien, S, Gisselbrecht, S

Blood 2003
11598010 Src transduces erythropoietin-induced differentiation signals through phosphatidylinositol 3-kinase

Kubota, Y, Kitanaka, A, Ishida, T, Kamano, H, Ohnishi, H, Waki, M, Tanaka, T, Okutani, Y

EMBO J. 2001
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