PKC phosphorylates ROBO3.1

Stable Identifier
R-HSA-9010681
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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PKC (PRKCA, and possibly other isoforms), recruited to ROBO3 receptor isoform ROBO3.1 by AKAP5 (AKAP79) phosphorylates ROBO3.1 on serine residue S1330 (Samelson et al. 2015).

Literature References
PubMed ID Title Journal Year
25882844 A-kinase Anchoring Protein 79/150 Recruits Protein Kinase C to Phosphorylate Roundabout Receptors

Samelson, BK, Gore, BB, Whiting, JL, Nygren, PJ, Purkey, AM, Colledge, M, Langeberg, LK, Dell'Acqua, ML, Zweifel, LS, Scott, JD

J. Biol. Chem. 2015
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein kinase C activity of ROBO3.1:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane]
Physical Entity
Activity
Orthologous Events
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