The enzyme ER Man I can slowly trim up to four of the mannoses on the N-glycan on unfolded proteins accumulated in the ER. This step describes the removal of the mannose in the A position (Hirao et al, 2006; Frenkel et al, 2003).
Gonzalez, DS, Karaveg, K, Vandersall-Nairn, AS, Lal, A, Moremen, KW
Avezov, E, Frenkel, Z, Ehrlich, M, Herscovics, A, Lederkremer, GZ
Karaveg, K, Siriwardena, A, Tempel, W, Liu, ZJ, Glushka, J, Wang, BC, Moremen, KW
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