A recently discovered protein called malectin is known to recognize the Glc(2)Man(9)GlcNAc(2) glycan (Schallus T et al, 2008). The exact role of this interaction is not clear but malectin is thought to regulate the availability of this substrate to glucosidase II, or to act as a chaperone to stabilize the unfolded protein.
Schallus, T, Jaeckh, C, Fehér, K, Palma, AS, Liu, Y, Simpson, JC, Mackeen, M, Stier, G, Gibson, TJ, Feizi, T, Pieler, T, Muhle-Goll, C
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