STUB1 (CHIP), an E3 ubiquitin ligase, promotes polyubiquitination of RUNX2, targeting it for proteasome-mediated degradation (Li et al. 2008).
Ren, F, Shi, Y, Zhai, Y, Irwin, DM, Li, X, Chang, Z, Shang, Y, Zheng, H, Huang, M, Chen, D, Wang, Y
ubiquitin protein ligase activity of RUNX2:STUB1 [cytosol]
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