FBXW7alpha, a component of an SCF ubiquitin ligase complex, binds to RUNX2 in the presence of GSK3B, probably after GSK3B phosphorylates RUNX2 (Kumar et al. 2015). The presence of other SCF complex components, besides FBXW7alpha, is assumed, although it has not been tested whether they co-immunoprecipitate with RUNX2 and GSK3B.
Khan, MP, Kumar, Y, Trivedi, AK, Kanaujiya, JK, Kapoor, I, Sanyal, S, Thacker, G, Khan, K, Chattopadhyay, N, Shukla, N
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