RUNX2 binds GSK3B

Stable Identifier
R-HSA-9008476
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RUNX2 binds GSK3B
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RUNX2 forms a complex with a serine/threonine kinase GSK3B. Since GSK3B can localize to both cytosol and nucleus, this reaction is shown to occur in the nucleoplasm, although this has not been experimentally tested (Kugimiya et al. 2007).
Literature References
PubMed ID Title Journal Year
17786208 GSK-3beta controls osteogenesis through regulating Runx2 activity

Woodgett, JR, Kawamura, N, Ohba, S, Kawaguchi, H, Kugimiya, F, Chung, UI, Nakamura, K, Chikuda, H, Azuma, Y, Hirata, M

PLoS ONE 2007
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Inferred From
Runx2 binds GSK3B (Mus musculus)
Authored
Orlic-Milacic, M  (2017-06-10)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2017-06-10)
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