TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen

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R-HSA-9008315
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Reaction [omitted]
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Homo sapiens
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The TGFA gene encodes the precursor of the transforming growth factor alpha (TGF alpha). Binding of the CITED1 to the promoter of the TGFA gene in the estrogen:ESR1-dependent manner stimulates TGFA transcription in MCF-7 breast cancer cell line (Yahata T et al. 2001).

Literature References
PubMed ID Title Journal Year
11581164 Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein

Yahata, T, Shao, W, Endoh, H, Hur, J, Coser, KR, Sun, H, Ueda, Y, Kato, S, Isselbacher, KJ, Brown, M, Shioda, T

Genes Dev. 2001
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