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ESR1 dimer:estrogen [nucleoplasm]
Stable Identifier
R-HSA-9008284
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Estrogen-dependent gene expression (Homo sapiens)
CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Homo sapiens)
CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Homo sapiens)
CITED1:EP300:ESR1:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
DDX5 binds ESR1:estrogen:TFF1 gene promoter (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1 binds to TFF1 gene promoter (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1 binds to TGFA gene promoter (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
Estrogen-responsive TFF1 gene expression (Homo sapiens)
ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1 [nucleoplasm] (Homo sapiens)
CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
Histone acetyltransferases are recruited to the TFF1 gene (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1 [nucleoplasm] (Homo sapiens)
CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1 [nucleoplasm] (Homo sapiens)
CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
NCOA1 binds ESR1:estrogen:TGFA gene (Homo sapiens)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
NCOA1 recruits EP300 to TGFA promoter (Homo sapiens)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFGA gene:NCOA1:EP300 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
NCOA3 binds ESR1:estrogen:TFGA gene (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:ERE:NCOA3:TFGA gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 (Homo sapiens)
ESR1:estrogen:ERE:NCOA3:EP300 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:ERE:NCOA3:TFGA gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:ERE:NCOA3:TFGA gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Homo sapiens)
ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen (Homo sapiens)
CITED1:EP300:ESR1:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:ERE:NCOA3:EP300 [nucleoplasm] (Homo sapiens)
ESR1:estrogen:ERE:NCOA3:TFGA gene [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
ESR1:estrogen:TFGA gene:NCOA1:EP300 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
ESR1 dimer:estrogen [nucleoplasm] (Homo sapiens)
Participants
components
2 x
E1, EST17b, estriol, estetrol [nucleoplasm]
2 x
ESR1 [nucleoplasm] (Homo sapiens)
Participant Of
input
ESR1 binds to TFF1 gene promoter
ESR1 binds to TGFA gene promoter
hasComponent
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm]
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm]
Inferred To
ESR1 dimer:estrogen [nucleoplasm] (Bos taurus)
ESR1 dimer:estrogen [nucleoplasm] (Canis familiaris)
ESR1 dimer:estrogen [nucleoplasm] (Danio rerio)
ESR1 dimer:estrogen [nucleoplasm] (Drosophila melanogaster)
ESR1 dimer:estrogen [nucleoplasm] (Gallus gallus)
ESR1 dimer:estrogen [nucleoplasm] (Mus musculus)
ESR1 dimer:estrogen [nucleoplasm] (Rattus norvegicus)
ESR1 dimer:estrogen [nucleoplasm] (Saccharomyces cerevisiae)
ESR1 dimer:estrogen [nucleoplasm] (Schizosaccharomyces pombe)
ESR1 dimer:estrogen [nucleoplasm] (Sus scrofa)
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
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