CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter

Stable Identifier
R-HSA-9008271
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
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CITED1 and EP300 contribute to the estrogen-dependent expression of the TGFA gene. CITED1 (also known as CBP) interacts directly with ESR1 through the transcriptional activation AF2 domain and enhances its activity. The interaction between ESR1 and exogenous CITED1 also stabilizes the interaction with EP300 (Yahate et al, 2001).

Literature References
PubMed ID Title Journal Year
11581164 Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein

Shioda, T, Brown, M, Kato, S, Endoh, H, Coser, KR, Isselbacher, KJ, Hur, J, Yahata, T, Sun, H, Shao, W, Ueda, Y

Genes Dev. 2001
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Orthologous Events
CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Bos taurus)
CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Canis familiaris)
CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Danio rerio)
CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Mus musculus)
CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Sus scrofa)
Authored
Shamovsky, V  (2017-06-20)
Reviewed
Magnani, L  (2018-02-23)
Created
Shamovsky, V  (2017-06-08)
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