E2F1 binds RAD51 gene promoter

Stable Identifier
R-HSA-9007561
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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E2F1 binds RAD51 gene promoter
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E2F1, presumably in complex with TFDP1 (DP-1) or TFDP2 (DP-2) binds the promoter of the RAD51 gene (Bertoli et al. 2013, Wu et al. 2014).

Literature References
PubMed ID Title Journal Year
24627085 Dynamic regulation of Rad51 by E2F1 and p53 in prostate cancer cells upon drug-induced DNA damage under hypoxia

Wu, M, Wang, X, McGregor, N, Pienta, KJ, Zhang, J

Mol. Pharmacol. 2014
23954429 Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription

Bertoli, C, Klier, S, McGowan, C, Wittenberg, C, de Bruin, RA

Curr. Biol. 2013
Participants
Input
Output
Participant Of
hasEvent
Authored
Orlic-Milacic, M  (2017-06-01)
Reviewed
Herlihy, A  (2017-05-12)
Created
Orlic-Milacic, M  (2017-05-31)
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