Reactome | UXT [nucleoplasm]

UXT [nucleoplasm]

Stable Identifier

R-HSA-9007484

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein UXT, UXT_HUMAN, ART-27, Androgen receptor trapped clone 27 protein

Locations in the PathwayBrowser for interactor UniProt:O95602 POLR1A

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External Reference Information

External Reference

UniProt:Q9UBK9 UXT

Gene Names

UXT, HSPC024

Chain

chain:1-157

Reference Genes

BioGPS Gene:8409 UXT

COSMIC (genes):UXT UXT

CTD Gene:8409 UXT

dbSNP Gene:8409 UXT

ENSEMBL:ENSG00000126756 UXT

ENSEMBL_homo_sapiens_GENE:ENSG00000126756.12 UXT

HGNC:12641 UXT

KEGG Gene (Homo sapiens):8409 UXT

Monarch:8409 UXT

NCBI Gene:8409 UXT

OMIM:300234 UXT

UCSC:Q9UBK9 UXT

Reference Transcript

Other Identifiers

11757419_a_at

17110495

218495_PM_at

218495_at

4007218

4007219

4007221

4007228

4007230

4007232

4007233

4007234

4007235

78679_at

8172358

8409

A_23_P159663

GE58325

GO:0000122

GO:0000226

GO:0000922

GO:0003682

GO:0003714

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0006351

GO:0006355

GO:0006915

GO:0007010

GO:0007018

GO:0007098

GO:0008017

GO:0008092

GO:0012501

GO:0043226

GO:0047497

GO:0048487

GO:0050821

GO:0101031

GO:0140110

GO:1990062

HMNXSV003005501

ILMN_1671314

ILMN_1745499

PH_hs_0010342

PH_hs_0031994

TC0X001000.hg

g4759297_3p_at

Participates

as an output of

UXT gene expression is repressed by the PRC1L4 complex (Homo sapiens)

Cross References

RefSeq

NP_004173.1, NP_705582.1

OpenTargets

ENSG00000126756

HPA

ENSG00000126756-UXT

GeneCards

Q9UBK9

Ensembl

ENSP00000327797, ENSP00000337393, ENSG00000126756, ENST00000333119, ENST00000335890

PRO

Q9UBK9

Pharos - Targets

Q9UBK9

Interactors (39)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.807	6
UniProt:P19388 POLR2E	2	POLR2E [nucleoplasm] (R-HSA-83713) POLR2E [cytosol] (R-HSA-1964438)	0.725	5
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.718	6
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.718	6
UniProt:Q9UHV9 PFDN2	1	PFDN2 [cytosol] (R-HSA-379544)	0.669	4
UniProt:Q9P286 PAK5	2	PAK7 [plasma membrane] (R-HSA-211555) PAK5 [cytosol] (R-HSA-428459)	0.666	4
UniProt:Q7Z3S9 NOTCH2NLA	1	NOTCH2NLA [extracellular region] (R-HSA-9908935)	0.666	4
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.643	3
UniProt:O15212 PFDN6	1	PFDN6 [cytosol] (R-HSA-379547)	0.643	3
UniProt:Q9NW08 POLR3B	2	POLR3B [cytosol] (R-HSA-1964435) POLR3B [nucleoplasm] (R-HSA-83702)	0.643	4
UniProt:P24928 POLR2A	7	p-S2,S7(CTD)-POLR2A [nucleoplasm] (R-HSA-6814543) p-S5,S7(CTD)-POLR2A [nucleoplasm] (R-HSA-6810226) p-S5(CTD)-POLR2A [nucleoplasm] (R-HSA-77100) Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm] (R-HSA-6781855) p-3S-POLR2A [nucleoplasm] (R-HSA-6797701) p-S2,S5(CTD)-POLR2A [nucleoplasm] (R-HSA-113420) POLR2A [nucleoplasm] (R-HSA-63502)	0.643	3
UniProt:Q04206 RELA	7	MeK310-RELA [nucleoplasm] (R-HSA-8865233) p-S536-RELA [nucleoplasm] (R-HSA-9861499) p-S276,5xAcK-RELA [nucleoplasm] (R-HSA-5660642) p-S276-RELA [nucleoplasm] (R-HSA-5624468) polySUMO3-K37,K122,K123-RELA [nucleoplasm] (R-HSA-4755466) RELA [cytosol] (R-HSA-168172) RELA [nucleoplasm] (R-HSA-177676)	0.639	5
UniProt:Q9H6T3 RPAP3			0.623	4
UniProt:P60328 KRTAP12-3	1	KRTAP12-3 [cytosol] (R-HSA-6810284)	0.601	4
UniProt:Q03112 MECOM	2	MECOM [cytosol] (R-HSA-5634790) MECOM [nucleoplasm] (R-HSA-8943897)	0.593	5
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.569	5
UniProt:Q8IUG1 KRTAP1-3	1	KRTAP1-3 [cytosol] (R-HSA-6809866)	0.556	3
UniProt:P26371 KRTAP5-9	1	KRTAP5-9 [cytosol] (R-HSA-6810265)	0.556	3
UniProt:P63172 DYNLT1	3	DYNLT1 [secretory granule lumen] (R-HSA-6801497) DYNLT1 [extracellular region] (R-HSA-6806509) DYNLT1 [ficolin-1-rich granule lumen] (R-HSA-6801487)	0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:Q8IUQ4 SIAH1	1	SIAH1 [cytosol] (R-HSA-374563)	0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:Q00013 MPP1	1	MPP1 [plasma membrane] (R-HSA-420423)	0.556	3
UniProt:Q6L8G8 KRTAP5-7	1	KRTAP5-7 [cytosol] (R-HSA-6810273)	0.556	3
UniProt:Q9H672 ASB7	1	ASB7 [cytosol] (R-HSA-975425)	0.527	2
UniProt:Q9NWS0 PIHD1			0.527	3
UniProt:Q96MX6 DAA10			0.527	3
UniProt:Q7KZ85 SUPT6H	1	SUPT6H [nucleoplasm] (R-HSA-8932908)	0.527	2
UniProt:O95602 POLR1A	1	POLR1A [nucleoplasm] (R-HSA-63494)	0.527	3
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.527	2
UniProt:P05423 POLR3D	2	POLR3D [nucleoplasm] (R-HSA-83704) POLR3D [cytosol] (R-HSA-1964429)	0.527	3
UniProt:Q9Y265 RUVBL1	1	RUVBL1 [nucleoplasm] (R-HSA-418323)	0.527	4
UniProt:Q8IXW5 RPAP2	1	RPAP2 [nucleoplasm] (R-HSA-6810227)	0.527	3
UniProt:Q9NUG6 PDRG1			0.527	3
UniProt:O14802 POLR3A	2	POLR3A [cytosol] (R-HSA-1964433) POLR3A [nucleoplasm] (R-HSA-83700)	0.527	3
UniProt:Q0D2N8 Q0D2N8			0.508	2
UniProt:P62140 PPP1CB	4	PPP1CB [cytosol] (R-HSA-163405) PPP1CB [nucleoplasm] (R-HSA-62003) PPP1CB P49R [cytosol] (R-HSA-9660547) PPP1CB A56P [cytosol] (R-HSA-9660543)	0.508	2
UniProt:Q15435 PP1R7			0.508	2

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