The PRC1L4 complex binds the CDC7 gene promoter

Stable Identifier
R-HSA-9007467
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The PRC1L4 complex, consisting of E2F6, CBX3 (HP1gamma), PCGF6 (MBLR), L3MBTL2, and RING1 (RING1A) or RNF2 (RING2, also known as RING1B), binds the promoter of the CDC7 gene (Trojer et al. 2011).
Literature References
PubMed ID Title Journal Year
21596310 L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure

Trojer, P, Gao, Z, Reinberg, D, Losson, R, Farnham, PJ, Xu, X, Li, Y, Li, G, Cao, AR, Zhang, J, Tempst, P, Erdjument-Bromage, H

Mol. Cell 2011
Participants
Participates
Authored
Reviewed
Created
Cite Us!