Pervasive developmental disorders

Stable Identifier
R-HSA-9005895
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Pervasive developmental disorders
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Pervasive developmental disorders (PDDs) largely overlap with the autism spectrum disorders (ASDs). PDDs manifest in childhood and mainly affect social interaction, including communication and behavior. PDDs can be caused by mutations in genes involved in brain development and function, environmental insults, or the combination of environmental factors and genetic susceptibility. The pervasive developmental disorder pathway that Reactome has annotated is the "Loss of function of MECP2 in Rett syndrome". For review of this topic, please refer to Picket and London 2005, Currenti 2010, Elsabbagh et al. 2012, Ferreri 2014.
Literature References
PubMed ID Title Journal Year
24855782 [Pervasive developmental disorders]

Ferreri, M

Rev Prat 2014
16254487 The neuropathology of autism: a review

Pickett, J, London, E

J. Neuropathol. Exp. Neurol. 2005
22495912 Global prevalence of autism and other pervasive developmental disorders

Elsabbagh, M, Divan, G, Koh, YJ, Kim, YS, Kauchali, S, Marcín, C, Montiel-Nava, C, Patel, V, Paula, CS, Wang, C, Yasamy, MT, Fombonne, E

Autism Res 2012
19774457 Understanding and determining the etiology of autism

Currenti, SA

Cell. Mol. Neurobiol. 2010
Participants
Events
Participates
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Disease
Name Identifier Synonyms
pervasive developmental disorder DOID:0060040 pervasive development disorder
Cross References
Mondo
Authored
Orlic-Milacic, M  (2017-10-02)
Created
Orlic-Milacic, M  (2017-05-11)
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