p-STAT1 dimer translocates from the cytosol to the nucleoplasm

Stable Identifier
R-HSA-8987218
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
Synonyms
p-STAT1 dimer translocates from the cytosol to the nucleoplasm after IL24 stimulus, stat1 translocates from the cytosol to the nucleoplasm
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p-STAT1 dimer translocates from the cytosol to the nucleoplasm
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Signal transducer and activator of transcription 1 alpha/beta (STAT1) dimer translocates from the cytosol to the nucleus after Interleukin-24 stimulus (IL24) (in BHK cells bearing IL 20RA/IL 20RB) (Parrish Novak et al. 2007). This is a black box event because the mechanism by which this event occurs (diffusion, transport) is unknown (Darnell 1997).

Literature References
PubMed ID Title Journal Year
12351624 Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions

Madden, K, Chandrasekher, YA, Yao, L, Brandt, C, Foster, DC, Jelinek, L, Brender, T, McKernan, PA, Jaspers, S, West, J, Jones, C, Parrish-Novak, J, Xu, W

J Biol Chem 2002
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Orthologous Events
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Bos taurus)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Caenorhabditis elegans)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Canis familiaris)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Danio rerio)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Dictyostelium discoideum)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Drosophila melanogaster)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Gallus gallus)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Mus musculus)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Rattus norvegicus)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Sus scrofa)
p-STAT1 dimer translocates from the cytosol to the nucleoplasm (Xenopus tropicalis)
Authored
Duenas, C  (2017-03-16)
Reviewed
Datta, SK  (2017-11-15)
Created
Duenas, C  (2017-05-05)
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