p-STAT3 dissociates from IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3

Stable Identifier
R-HSA-8987156
Type
Reaction [uncertain]
Species
Homo sapiens
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Phosphorylated Signal transducer and activator of transcription 5A or 5B (STAT5) dissociates from the Interleukin-20 (IL20) receptor complex (Tristaris et al. 2007). This is a black box event because dissociation is inferred from the signalling events of other Interleukins where phosphorylated STATs translocate to the nucleus, as with Interleukin-3 (Hirose et al. 2014).

Literature References
PubMed ID Title Journal Year
17878297 IL-20 is an arteriogenic cytokine that remodels collateral networks and improves functions of ischemic hind limbs

Tritsaris, K, Myren, M, Ditlev, SB, H├╝bschmann, MV, van der Blom, I, Hansen, AJ, Olsen, UB, Cao, R, Zhang, J, Jia, T, Wahlberg, E, Dissing, S, Cao, Y

Proc. Natl. Acad. Sci. U.S.A. 2007
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