Signal transducer and activator of transcription 1alpha/beta (STAT1) is believed to dimerize after it dissociates from the Interleukin-24 (IL24) receptor complex. This is a black box event because dimerization is inferred from STAT1 dimerization in response to Interferon gamma (IFNG) (Wehinger et al. 1996) and the observed translocation of STAT1 to the nucleus in response to IL24 (Parrish-Novak et al. 2002).
Wehinger, J, Gouilleux, F, Groner, B, Finke, J, Mertelsmann, R, Weber-Nordt, RM
Parrish-Novak, J, Xu, W, Brender, T, Yao, L, Jones, C, West, J, Brandt, C, Jelinek, L, Madden, K, McKernan, PA, Foster, DC, Jaspers, S, Chandrasekher, YA
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