RUNX2 binds GLI2

Stable Identifier
R-HSA-8986294
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RUNX2 binds GLI2
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GLI2, activated in response to Indian Hedgehog (IHH) signaling, forms a complex with RUNX2 and enhances transcriptional activity of RUNX2 (Shimoyama et al. 2007).

Literature References
PubMed ID Title Journal Year
17442891 Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function

Yamaguchi, A, Noda, M, Yoneda, T, Amano, K, Hata, K, Matsubara, T, Wada, M, Nishimura, R, Shimoyama, A, Nifuji, A, Ikeda, F

Mol. Biol. Cell 2007
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Inferred From
Runx2 binds Gli2 (Mus musculus)
Authored
Orlic-Milacic, M  (2017-04-24)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2017-04-24)
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