Reactome | NDUFB8(1-28) [mitochondrial matrix]

NDUFB8(1-28) [mitochondrial matrix]

Stable Identifier

R-HSA-8986166

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

NDUFB8 transit peptide, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial, NDUB8_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O95169 NDUFB8

Gene Names

NDUFB8

Chain

transit peptide:1-28, chain:29-186

Reference Genes

BioGPS Gene:4714 NDUFB8

COSMIC (genes):NDUFB8 NDUFB8

CTD Gene:4714 NDUFB8

dbSNP Gene:4714 NDUFB8

ENSEMBL:ENSG00000166136 NDUFB8

ENSEMBL_homo_sapiens_GENE:ENSG00000166136.16 NDUFB8

HGNC:7703 NDUFB8

KEGG Gene (Homo sapiens):4714 NDUFB8

Monarch:4714 NDUFB8

NCBI Gene:4714 NDUFB8

OMIM:602140 NDUFB8

UCSC:O95169 NDUFB8

Reference Transcript

Other Identifiers

11716414_a_at

11716415_s_at

201226_PM_at

201226_at

201227_PM_s_at

201227_s_at

214241_PM_at

214241_at

32774_at

3303531

3303532

3303533

3303534

3303537

3303538

3303539

3303540

3303541

3303542

3543747

3729290

4714

7935810

A_24_P346886

A_33_P3384721

GE80107

GE86517

GO:0003824

GO:0005215

GO:0005739

GO:0005743

GO:0005747

GO:0005759

GO:0005783

GO:0006091

GO:0006120

GO:0007005

GO:0008137

GO:0009060

GO:0016020

GO:0016491

GO:0032981

GO:0042776

GO:0043226

GO:0055086

GO:0065003

GO:0070469

GO:1901135

HMNXSV003002485

ILMN_1661170

g4826853_3p_a_at

Participates

as a member of

Mitochondrial targeting peptides (from inner membrane proteins) [mitochondrial matrix] (Homo sapiens)

Other forms of this molecule

NDUFB8 [mitochondrial inner membrane]

NDUFB8(1-186) [mitochondrial inner membrane]

NDUFB8(1-186) [mitochondrial intermembrane space]

Inferred To

ndufb8 [mitochondrial matrix] (Danio rerio)

NDUFB8(1-28) [mitochondrial matrix] (Dictyostelium discoideum)

ND-ASHI [mitochondrial matrix] (Drosophila melanogaster)

NDUFB8 [mitochondrial matrix] (Bos taurus)

NDUFB8 [mitochondrial matrix] (Canis familiaris)

NDUFB8 [mitochondrial matrix] (Gallus gallus)

NDUFB8 [mitochondrial matrix] (Sus scrofa)

ndub-8 [mitochondrial matrix] (Caenorhabditis elegans)

Ndufb8 [mitochondrial matrix] (Mus musculus)

Ndufb8 [mitochondrial matrix] (Rattus norvegicus)

Cross References

RefSeq

NP_001271296.1, NP_004995.1, NP_001271297.1

OpenTargets

ENSG00000166136

GeneCards

O95169

HPA

ENSG00000166136-NDUFB8

Ensembl

ENSP00000299166, ENST00000370322, ENST00000370320, ENSG00000166136, ENSP00000359346, ENST00000299166, ENSP00000359344

PRO

O95169

Pharos - Targets

O95169

HMDB Protein

HMDBP00200

PDB

5XTI, 5XTD, 5XTH, 5XTC

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.725	5
UniProt:O75380 NDUFS6	1	NDUFS6 [mitochondrial inner membrane] (R-HSA-163922)	0.527	4
UniProt:Q9BQ95 ECSIT	2	ECSIT [cytosol] (R-HSA-168064) ECSIT [mitochondrial inner membrane] (R-HSA-5689047)	0.527	2
UniProt:Q9UI09 NDUFA12	1	NDUFA12 [mitochondrial inner membrane] (R-HSA-59864)	0.527	2
UniProt:O43920 NDUFS5	1	NDUFS5 [mitochondrial inner membrane] (R-HSA-60226)	0.527	3
UniProt:O43181 NDUFS4	1	NDUFS4 [mitochondrial inner membrane] (R-HSA-163946)	0.527	2
UniProt:Q6UWR7 ENPP6	1	ENPP6 [plasma membrane] (R-HSA-6814799)	0.527	2
UniProt:P25103 TACR1	2	TACR1 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869122) TACR1 [plasma membrane] (R-HSA-380103)	0.527	2
UniProt:P19526 FUT1	1	FUT1 [Golgi membrane] (R-HSA-9034059)	0.527	3

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