Reactome | PITRM1 [mitochondrial matrix]

PITRM1 [mitochondrial matrix]

Stable Identifier

R-HSA-8986159

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Presequence protease, mitochondrial, PREP_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q5JRX3 PITRM1

Gene Names

PITRM1, KIAA1104, MP1, PREP

Chain

transit peptide:1-28, chain:29-1037

Reference Genes

BioGPS Gene:10531 PITRM1

COSMIC (genes):PITRM1 PITRM1

CTD Gene:10531 PITRM1

dbSNP Gene:10531 PITRM1

ENSEMBL:ENSG00000107959 PITRM1

ENSEMBL:ENSG00000107959.17 PITRM1

HGNC:17663 PITRM1

KEGG Gene (Homo sapiens):10531 PITRM1

Monarch:10531 PITRM1

NCBI Gene:10531 PITRM1

OMIM:618211 PITRM1

UCSC:Q5JRX3 PITRM1

Reference Transcript

Other Identifiers

10531

11725613_x_at

11745253_a_at

11745942_a_at

11746526_a_at

16711205

205273_PM_s_at

205273_s_at

3274175

3274176

3274177

3274179

3274181

3274182

3274186

3274190

3274191

3274192

3274193

3274195

3274197

3274200

3274202

3274204

3274205

3274206

3274208

3274210

3274211

3274212

3274213

3274215

3274216

3274217

3274218

3274219

3274220

3274222

3274224

3274225

34839_at

7931778

A_33_P3265104

GO:0003824

GO:0004222

GO:0005515

GO:0005739

GO:0005759

GO:0006508

GO:0006626

GO:0006886

GO:0007005

GO:0008047

GO:0008233

GO:0008237

GO:0008270

GO:0016485

GO:0016787

GO:0043226

GO:0046872

GO:0051604

GO:0098772

GO:0140096

HMNXSV003017887

HMNXSV003052348

ILMN_1698072

PH_hs_0022064

TC10000975.hg

g7662487_3p_s_at

Inferred To

ucr-2.3 [mitochondrial matrix] (Caenorhabditis elegans)

Homologues of PITRM1 [mitochondrial matrix] (Xenopus tropicalis)

PITRM1 [mitochondrial matrix] (Bos taurus)

PITRM1 [mitochondrial matrix] (Canis familiaris)

PITRM1 [mitochondrial matrix] (Danio rerio)

PITRM1 [mitochondrial matrix] (Drosophila melanogaster)

PITRM1 [mitochondrial matrix] (Gallus gallus)

PITRM1 [mitochondrial matrix] (Mus musculus)

PITRM1 [mitochondrial matrix] (Saccharomyces cerevisiae)

PITRM1 [mitochondrial matrix] (Schizosaccharomyces pombe)

PITRM1 [mitochondrial matrix] (Sus scrofa)

PITRM1 [mitochondrial matrix] (Xenopus tropicalis)

pitrm1 [mitochondrial matrix] (Dictyostelium discoideum)

spire2 [mitochondrial matrix] (Xenopus tropicalis)

Pitrm1 [mitochondrial matrix] (Rattus norvegicus)

Cross References

RefSeq

NP_001229236.1, NP_055704.2, NP_001229238.1

OpenTargets

ENSG00000107959

HPA

ENSG00000107959-PITRM1

GeneCards

Q5JRX3

ZINC target

Q5JRX3

Ensembl

ENSP00000224949, ENST00000451104, ENSP00000370377, ENSG00000107959, ENSP00000401201, ENST00000224949, ENST00000380989

PRO

Q5JRX3

Pharos - Targets

Q5JRX3

PDB

6XOU, 6XOS, 6XOW, 4L3T, 6XOT, 6XOV, 4NGE, 4RPU

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.643	3
UniProt:Q80H93 8b	1	8b [cytosol] (R-COV-9678168)	0.527	2
UniProt:A6NGG8 PCARE			0.508	2
UniProt:Q83D60 Q83D60			0.488	2

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