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OTC(1-354) [mitochondrial inner membrane]
Stable Identifier
R-HSA-8986146
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
OTC preprotein, Ornithine carbamoyltransferase, mitochondrial ecNumber2.1.3.3/ecNumber, OTC_HUMAN
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Mitochondrial protein import (Homo sapiens)
MPP cleaves targeting peptide (presequence) of matrix precursors (Homo sapiens)
TIMM23 PAM:Precursor Cargo [mitochondrial inner membrane] (Homo sapiens)
Precursor Cargo of TIMM23 PAM [mitochondrial inner membrane] (Homo sapiens)
OTC(1-354) [mitochondrial inner membrane] (Homo sapiens)
Precursor proteins enter TIMM23 PAM (Homo sapiens)
TIMM23 PAM:Precursor Cargo [mitochondrial inner membrane] (Homo sapiens)
Precursor Cargo of TIMM23 PAM [mitochondrial inner membrane] (Homo sapiens)
OTC(1-354) [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P00480 OTC
Gene Names
OTC
Chain
transit peptide:1-32, chain:33-354
Reference Genes
BioGPS Gene:5009 OTC
COSMIC (genes):OTC OTC
CTD Gene:5009 OTC
dbSNP Gene:5009 OTC
ENSEMBL:ENSG00000036473 OTC
HGNC:8512 OTC
KEGG:hsa:5009 OTC
Monarch:5009 OTC
NCBI Gene:5009 OTC
OMIM:300461 OTC
UCSC:P00480 OTC
Reference Transcript
RefSeq:NM_000531.5 OTC
Other Identifiers
11740020_at
17102592
207200_PM_at
207200_at
35111_at
3973971
3973972
3973973
3973974
3973975
3973976
3973979
3973984
3973985
3973986
3973987
3973988
3973994
3973995
3973996
3973997
3973998
3973999
3974000
5009
683_at
8166769
A_14_P118950
A_23_P257355
GE57536
GO:0000050
GO:0001889
GO:0003824
GO:0004585
GO:0005543
GO:0005739
GO:0005743
GO:0005759
GO:0006520
GO:0006526
GO:0006591
GO:0006593
GO:0007494
GO:0008289
GO:0008652
GO:0009410
GO:0010043
GO:0016597
GO:0016740
GO:0016743
GO:0019240
GO:0031667
GO:0032868
GO:0042301
GO:0042450
GO:0042802
GO:0043226
GO:0048856
GO:0055081
GO:0070781
GO:0071941
GO:0097272
HMNXSV003032799
ILMN_1749114
K02100_at
PH_hs_0006412
TC0X000177.hg
g9257233_3p_at
Participates
as a member of
Precursor Cargo of TIMM23 PAM [mitochondrial inner membrane] (Homo sapiens)
Other forms of this molecule
OTC(1-354) [mitochondrial intermembrane space]
OTC [mitochondrial inner membrane]
OTC(1-32) [mitochondrial matrix]
OTC [mitochondrial matrix]
Cross References
ENSEMBL
ENST00000039007
,
ENSP00000039007
OpenTargets
ENSG00000036473
ZINC - Substances
OTC_HUMAN
ZINC - Biogenic
OTC_HUMAN
ZINC target
P00480
PRO
P00480
PDB
1C9Y
,
1OTH
,
1EP9
,
1FVO
ZINC - Metabolites
OTC_HUMAN
IntEnz
2.1.3.3
HPA
ENSG00000036473-OTC
Pharos - Targets
P00480
Orphanet
OTC
ZINC - Predictions - Purchasable
OTC_HUMAN
HMDB Protein
HMDBP00927
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96I59 NARS2
1
NARS2 [mitochondrial matrix]
(R-HSA-379585)
0.527
2
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