IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5

Stable Identifier
R-HSA-8985988
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
STAT1, STAT3 or STAT5 are phosphorylated by IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3
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Signal transducer and activator of transcription 1-alpha/beta (STAT1), STAT3, and STAT5A/STAT5B (collectively termed STAT5) are tyrosine phosphorylated in tyrosine residues 701, 705 and 649 respectively, in response to IL9 stimulation (Nizsalóczki et al. 2014, Yamasaki et al. 2010, Demoulin et al. 2001).

Literature References
PubMed ID Title Journal Year
11306517 Interleukin-9 (IL-9) induces cell growth arrest associated with sustained signal transducer and activator of transcription activation in lymphoma cells overexpressing the IL-9 receptor

Demoulin, JB, Van Snick, J, Renauld, JC

Cell Growth Differ. 2001
25297818 Distinct spatial relationship of the interleukin-9 receptor with interleukin-2 receptor and major histocompatibility complex glycoproteins in human T lymphoma cells

Nizsalóczki, E, Csomós, I, Nagy, P, Fazekas, Z, Goldman, CK, Waldmann, TA, Damjanovich, S, Vámosi, G, Mátyus, L, Bodnár, A

Chemphyschem 2014
20169197 IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells

Yamasaki, A, Saleh, A, Koussih, L, Muro, S, Halayko, AJ, Gounni, AS

PLoS ONE 2010
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