p-Y649-STAT5A, p-STAT5B dimerizes

Stable Identifier
R-HSA-8985950
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
cytosol
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p-Y649-STAT5A, p-STAT5B dimerizes
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Phosphorylated Signal transducer and activator of transcription 5A/B (STAT5) homodimerizes.

Following IL9 induced STAT activation, homodimers of tyrosine phosphorylated STAT5 have been identified (Bauer et al. 1998).

Literature References
PubMed ID Title Journal Year
9535918 Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and prevention of apoptosis

You, Y, Bauer, JH, Lai, SY, Liu, KD, Goldsmith, MA

J. Biol. Chem. 1998
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Orthologous Events
p-Y649-STAT5A, p-STAT5B dimerizes (Caenorhabditis elegans)
p-Y649-STAT5A, p-STAT5B dimerizes (Canis familiaris)
p-Y649-STAT5A, p-STAT5B dimerizes (Danio rerio)
p-Y649-STAT5A, p-STAT5B dimerizes (Dictyostelium discoideum)
p-Y649-STAT5A, p-STAT5B dimerizes (Drosophila melanogaster)
p-Y649-STAT5A, p-STAT5B dimerizes (Gallus gallus)
p-Y649-STAT5A, p-STAT5B dimerizes (Mus musculus)
p-Y649-STAT5A, p-STAT5B dimerizes (Rattus norvegicus)
p-Y649-STAT5A, p-STAT5B dimerizes (Sus scrofa)
Authored
Duenas, C  (2017-04-21)
Reviewed
Meldal, BH  (2016-01-28)
Limon, PL  (2018-04-27)
Created
Duenas, C  (2017-04-21)
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