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IL2RG:p-Y904,939-JAK3 [plasma membrane]
Stable Identifier
R-HSA-8985933
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-2 family signaling (Homo sapiens)
Interleukin-9 signaling (Homo sapiens)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Homo sapiens)
IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Homo sapiens)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Homo sapiens)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Homo sapiens)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Homo sapiens)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Homo sapiens)
IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Homo sapiens)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Homo sapiens)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Homo sapiens)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
18250158
Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity
Frost, JA
,
Kirken, RA
,
Cheng, H
,
Ross, JA
Mol. Cell. Biol.
2008
Participants
components
IL2RG [plasma membrane]
(Homo sapiens)
p-Y904,939-JAK3 [plasma membrane]
(Homo sapiens)
Participates
as a component of
IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [plasma membrane] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Homo sapiens)
Inferred To
IL2RG:p-Y904,939-JAK3 [plasma membrane]
(Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane]
(Canis familiaris)
IL2RG:p-Y904,939-JAK3 [plasma membrane]
(Gallus gallus)
IL2RG:p-Y904,939-JAK3 [plasma membrane]
(Mus musculus)
IL2RG:p-Y904,939-JAK3 [plasma membrane]
(Rattus norvegicus)
IL2RG:p-Y904,939-JAK3 [plasma membrane]
(Sus scrofa)
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