Reactome | ZCCHC8 [nucleoplasm]

ZCCHC8 [nucleoplasm]

Stable Identifier

R-HSA-8985573

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Zinc finger CCHC domain-containing protein 8, TRAMP-like complex RNA-binding factor ZCCHC8

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q6NZY4 ZCCHC8

Gene Names

ZCCHC8

Chain

initiator methionine:, chain:2-707

Reference Genes

BioGPS Gene:55596 ZCCHC8

COSMIC (genes):ZCCHC8 ZCCHC8

CTD Gene:55596 ZCCHC8

dbSNP Gene:55596 ZCCHC8

ENSEMBL:ENSG00000033030 ZCCHC8

HGNC:25265 ZCCHC8

KEGG:hsa:55596 ZCCHC8

Monarch:55596 ZCCHC8

NCBI Gene:55596 ZCCHC8

OMIM:616381 ZCCHC8

UCSC:Q6NZY4 ZCCHC8

Reference Transcript

RefSeq:NM_017612.4 ZCCHC8

Other Identifiers

11729668_at

16771727

218478_PM_s_at

218478_s_at

230786_PM_at

230786_at

3475680

3475681

3475682

3475683

3475684

3475685

3475686

3475687

3475689

3475690

3475692

3475693

3475694

3475695

3475696

3475697

3475698

3475699

3475700

3475701

3475705

3475706

3475707

3475708

3475709

3475710

3475711

3475712

3475713

3475714

55596

56080_at

64115_at

7967287

A_23_P64669

GE56817

GE898864

GO:0000398

GO:0003676

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0006396

GO:0006397

GO:0008270

GO:0008380

GO:0016071

GO:0016073

GO:0016076

GO:0016604

GO:0031124

GO:0031499

GO:0043226

GO:0046872

GO:0071013

HMNXSV003009698

Hs.99298.0.A1_3p_at

ILMN_1792092

PH_hs_0031167

TC12002074.hg

g8922133_3p_a_at

Participates

as a component of

RBM7:ZCCHC8:SKIV2L2 [nucleoplasm] (Homo sapiens)

Inferred To

ZCCHC8 [nucleoplasm] (Bos taurus)

ZCCHC8 [nucleoplasm] (Caenorhabditis elegans)

ZCCHC8 [nucleoplasm] (Canis familiaris)

ZCCHC8 [nucleoplasm] (Drosophila melanogaster)

ZCCHC8 [nucleoplasm] (Gallus gallus)

ZCCHC8 [nucleoplasm] (Sus scrofa)

Zcchc8 [nucleoplasm] (Mus musculus)

Zcchc8 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of ZCCHC8 [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of ZCCHC8 [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of ZCCHC8 [nucleoplasm] (Schizosaccharomyces pombe)

zcchc8 [nucleoplasm] (Danio rerio)

zcchc8 [nucleoplasm] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000543897, ENSP00000488055, ENST00000633063, ENSP00000441423, ENSG00000033030, ENSP00000438993, ENST00000536306

OpenTargets

ENSG00000033030

GeneCards

ZCCHC8

HPA

ENSG00000033030-ZCCHC8

PRO

Q6NZY4

Pharos - Targets

Q6NZY4

GlyGen

Q6NZY4

PDB

7S7C, 5LXR, 7S7B, 7Z4Z, 7Z4Y, 6C90, 7Z52, 5LXY

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y580 RBM7	1	RBM7 [nucleoplasm] (R-HSA-8985564)	0.858	13
UniProt:P52298 NCBP2	2	NCBP2 [nucleoplasm] (R-HSA-51463) NCBP2 [cytosol] (R-HSA-162458)	0.643	3
UniProt:Q86VM9 ZC3H18	1	ZC3H18 [nucleoplasm] (R-HSA-9930040)	0.643	8
UniProt:Q9NQT4 EXOSC5	3	EXOSC5 [cytosol] (R-HSA-429889) EXOSC5 [nucleoplasm] (R-HSA-6791550) EXOSC5 [nucleolus] (R-HSA-9935829)	0.527	3
UniProt:Q13901 C1D	2	C1D [nucleoplasm] (R-HSA-6791515) C1D [nucleolus] (R-HSA-9935822)	0.527	3
UniProt:P38398 BRCA1	20	polySUMO2,3-BRCA1 [nucleoplasm] (R-HSA-2997624) monoSUMO1-K109-BRCA1 [nucleoplasm] (R-HSA-2997644) BRCA1 M1411T [nucleoplasm] (R-HSA-9702140) BRCA1 M1400V [nucleoplasm] (R-HSA-9701202) BRCA1 L1407P [nucleoplasm] (R-HSA-9702135) BRCA1 Y777* [nucleoplasm] (R-HSA-9702765) BRCA1 S1009* [nucleoplasm] (R-HSA-9702755) BRCA1 P724Lfs12 [nucleoplasm] (R-HSA-9703778) BRCA1 S451 [nucleoplasm] (R-HSA-9702754) BRCA1 S864* [nucleoplasm] (R-HSA-9702752) BRCA1 P897Kfs5 [nucleoplasm] (R-HSA-9703782) BRCA1 N555Kfs17 [nucleoplasm] (R-HSA-9703781) BRCA1 Y1127Sfs6 [nucleoplasm] (R-HSA-9703780) BRCA1 S886Cfs16 [nucleoplasm] (R-HSA-9703802) BRCA1 V83Cfs2 [nucleoplasm] (R-HSA-9703800) BRCA1 T464Pfs11 [nucleoplasm] (R-HSA-9703807) BRCA1 G813Dfs2 [nucleoplasm] (R-HSA-9703549) BRCA1 V340Gfs6 [nucleoplasm] (R-HSA-9703804) BRCA1 Y655* [nucleoplasm] (R-HSA-9702769) BRCA1 W372* [nucleoplasm] (R-HSA-9702768)	0.524	2
UniProt:Q16629 SRSF7	1	SRSF7 [nucleoplasm] (R-HSA-72029)	0.483	2