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PDE12 [cytosol]
Stable Identifier
R-HSA-8985572
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
OAS antiviral response (Homo sapiens)
PDE12 cleaves 2'-5' oligoadenylates (Homo sapiens)
PDE12 [cytosol] (Homo sapiens)
RNASEL binds 2'-5' oligoadenylate (Homo sapiens)
PDE12 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6L8Q7 PDE12
Gene Names
PDE12
Chain
transit peptide:1-42, chain:43-609
Reference Genes
BioGPS Gene:201626 PDE12
COSMIC (genes):PDE12 PDE12
CTD Gene:201626 PDE12
dbSNP Gene:201626 PDE12
ENSEMBL:ENSG00000174840 PDE12
HGNC:25386 PDE12
KEGG:hsa:201626 PDE12
Monarch:201626 PDE12
NCBI Gene:201626 PDE12
OMIM:616519 PDE12
UCSC:Q6L8Q7 PDE12
Reference Transcript
RefSeq:NM_177966.6 PDE12
Other Identifiers
106144532
11739235_at
11739236_at
11739237_s_at
1554915_PM_a_at
1554915_a_at
16942042
16942052
201626
214826_3p_at
214826_PM_at
214826_at
231839_3p_at
231839_PM_at
231839_at
2625678
2625680
2625682
2625684
2625686
2625688
2625690
2625692
2625694
2625696
2625698
2625700
2625702
2625704
2625706
2625708
2625710
2625712
2625714
2625716
2625718
2625732
2625734
2625736
2625738
2625740
2625742
2625744
2625762
2625768
2625770
2625772
38144_at
61604_at
8080676
81599_at
85054_at
A_14_P121474
A_14_P126614
A_23_P343914
A_24_P230708
A_32_P165836
A_33_P3288017
GE552536
GE55818
GO:0000175
GO:0000288
GO:0000958
GO:0002376
GO:0003824
GO:0004527
GO:0004535
GO:0005739
GO:0005759
GO:0005829
GO:0006397
GO:0016071
GO:0016787
GO:0034611
GO:0035457
GO:0043226
GO:0044528
GO:0045070
GO:0046872
GO:0051607
GO:0071346
GO:0071359
GO:0090304
GO:0098542
GO:0140098
GO:0140374
HMNXSV003010141
HMNXSV003014899
Hs.151293.0.S1_3p_s_at
Hs.151293.0.S1_3p_x_at
Hs.307238.0.S1_3p_at
Hs.307238.0.S1_3p_x_at
Hs2.151293.1.S1_3p_s_at
ILMN_1660305
PH_hs_0009122
TC03000369.hg
TC03000371.hg
p11816
This entity regulates
Negatively
RNASEL binds 2'-5' oligoadenylate
(Homo sapiens)
Inferred To
pde-12 [cytosol]
(Caenorhabditis elegans)
d3635 [cytosol]
(Drosophila melanogaster)
PDE12 [cytosol]
(Bos taurus)
PDE12 [cytosol]
(Canis familiaris)
PDE12 [cytosol]
(Gallus gallus)
PDE12 [cytosol]
(Mus musculus)
PDE12 [cytosol]
(Rattus norvegicus)
PDE12 [cytosol]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
3207
ENSEMBL
ENSP00000309142
,
ENST00000311180
OpenTargets
ENSG00000174840
HPA
ENSG00000174840-PDE12
PRO
Q6L8Q7
Pharos - Targets
Q6L8Q7
GlyGen
Q6L8Q7
PDB
4Z2B
,
4Z0V
,
4ZKF
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