OAS1 oligomerizes

Stable Identifier
R-HSA-8983688
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Tick-borne encephalitis virus, Dengue virus, West Nile virus
Compartment
cytosol
ReviewStatus
5/5
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OAS1 oligomerizes
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The tetramerization of 2'-5'-oligoadenylate synthetase OAS1 is required for enzymatic activity (Ghosh A et al. 1997).
Literature References
PubMed ID Title Journal Year
9407111 Enzymatic activity of 2'-5'-oligoadenylate synthetase is impaired by specific mutations that affect oligomerization of the protein

Sarkar, SN, Guo, W, Sen, GC, Ghosh, A, Bandyopadhyay, S

J. Biol. Chem. 1997
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Authored
Shamovsky, V  (2017-03-27)
Reviewed
D'Eustachio, P  (2017-12-02)
Silverman, RH  (2018-07-31)
Created
Shamovsky, V  (2017-03-27)
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