OAS1 oligomerizes

Stable Identifier
R-HSA-8983688
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Dengue virus, Tick-borne encephalitis virus, West Nile virus
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The tetramerization of 2'-5'-oligoadenylate synthetase OAS1 is required for enzymatic activity (Ghosh A et al. 1997).

Literature References
PubMed ID Title Journal Year
9407111 Enzymatic activity of 2'-5'-oligoadenylate synthetase is impaired by specific mutations that affect oligomerization of the protein

Ghosh, A, Sarkar, SN, Guo, W, Bandyopadhyay, S, Sen, GC

J. Biol. Chem. 1997
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