TSLP binds CRLF2:IL7R

Stable Identifier
R-HSA-8983061
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
Synonyms
TSLP binds TSLPR1:IL7R
ReviewStatus
5/5
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TSLP binds CRLF2:IL7R
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The functional receptor for human Thymic stromal lymphopoietin (TSLP) consists of two subunits, Cytokine receptor-like factor 2 (TSLPR) and Interleukin-7 receptor subunit alpha (IL7R) (Reche et al.2001).
This is a black box event since it is not clear whether this binding event occurs in association with other IL7 receptor complexes or independently.
Literature References
PubMed ID Title Journal Year
11418668 Human thymic stromal lymphopoietin preferentially stimulates myeloid cells

Bazan, JF, Johnston, J, Zurawski, SM, de Waal Malefyt, R, Gorman, DM, Liu, MR, Liu, YJ, Clifford, T, Kastelein, RA, Travis, M, Spits, H, Soumelis, V, Reche, PA

J. Immunol. 2001
Participants
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Output
Participates
as an event of
Orthologous Events
TSLP binds CRLF2:IL7R (Canis familiaris)
Authored
Duenas, C  (2017-07-20)
Reviewed
Kumar, U  (2017-07-26)
Created
Duenas, C  (2017-03-22)
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