Inferred from mouse:Following binding of TSLP to Cytokine receptor-like factor 2 (CRLF2, TSLPR) and Interleukin-7 receptor subunit alpha (IL7R), Signal transducer and activator of transcription 5A and 5B (STAT5A and STAT5B) and Signal transducer and activator of transcription 3 (STAT3) were phosphorylated in various Ba/F3 cell populations (Reche et al. 2001).This is a black box event since the kinase responsible for STAT phosphorylation is unknown.
Bazan, JF, Johnston, J, Zurawski, SM, de Waal Malefyt, R, Gorman, DM, Liu, MR, Liu, YJ, Clifford, T, Kastelein, RA, Travis, M, Spits, H, Soumelis, V, Reche, PA
transmembrane receptor protein kinase activity of IL7R:TSLP:CRLF2:STAT3 [plasma membrane]
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