Myoglobin:oxygen dissociates

Stable Identifier
R-HSA-8981622
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

When the concentration of oxygen is low myoglobin:oxygen dissociates to yield free oxygen (Rossi-Fanelli and Antonini 1958, Boulton and Huntsman 1972, Wang et al. 2004). The dissociation constant is about 1 micromole per liter. Myoglobin:oxygen may also transfer oxygen directly to cytochrome oxidase of mitochondria (inferred from rat homologs in Yamada et al. 2013).

Literature References
PubMed ID Title Journal Year
15601759 Human myoglobin recognition of oxygen: dynamics of the energy landscape

Wang, Y, Baskin, JS, Xia, T, Zewail, AH

Proc. Natl. Acad. Sci. U.S.A. 2004
5032105 Variants of human myoglobin: their oxygen dissociation curves

Boulton, FE, Huntsman, RG

Br. J. Haematol. 1972
13584010 Studies on the oxygen and carbon monoxide equilibria of human myoglobin

ROSSI-FANELLI, A, ANTONINI, E

Arch. Biochem. Biophys. 1958
23195625 Interaction between myoglobin and mitochondria in rat skeletal muscle

Yamada, T, Furuichi, Y, Takakura, H, Hashimoto, T, Hanai, Y, Jue, T, Masuda, K

J. Appl. Physiol. 2013
Participants
Participant Of
Event Information
Orthologous Events
Authored
Reviewed
Created
Cite Us!