GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol

Stable Identifier
R-HSA-8981553
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The SLC2A14 gene appears to have arisen by duplication of the SLC2A3 gene. It is expressed only in testis. The GLUT14 / SLC2A14 protein product has not been characterized but is inferred based on sequence similarity to exist as a plasma membrane associated tetramer that mediates the facilitated diffusion of glucose (Glc) into cells (Wu & Freeze 2002).

Literature References
PubMed ID Title Journal Year
12504846 GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms

Wu, X, Freeze, HH

Genomics 2002
Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
D-glucose transmembrane transporter activity of GLUT14 / SLC2A14 tetramer [plasma membrane]
Physical Entity
Activity
Orthologous Events
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Reviewed
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