CIT-3 binds activated RHOA, RHOB, RHOC and RAC1

Stable Identifier
R-HSA-8981443
Type
Reaction
Species
Homo sapiens
Compartment
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The neuronally expressed CIT isoform, CIT-3 (CIT-N), lacks the kinase domain but retains the RHO GTPase binding domain (Di Cunto et al. 1998) and can bind to activated GTP-bound RHOA, RHOB, RHOC and RAC1.

Literature References
PubMed ID Title Journal Year
9792683 Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron

Calautti, E, Turco, E, Di Cunto, F, Ong, L, Dotto, GP, Topley, G, Hsiao, J

J. Biol. Chem. 1998
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