The neuronally expressed CIT isoform, CIT-3 (CIT-N), lacks the kinase domain but retains the RHO GTPase binding domain (Di Cunto et al. 1998) and can bind to activated GTP-bound RHOA, RHOB, RHOC and RAC1.
Di Cunto, F, Calautti, E, Hsiao, J, Ong, L, Topley, G, Turco, E, Dotto, GP
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