p-STAT5A

Stable Identifier
R-HSA-8980151
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Inferred from mouse: Interleukin-25 (IL25 or IL17E) stimulation had any effect on the phosphorylation of STAT proteins. Although IL25 had no effect on the activation of Signal transducer and activator of transcription 6 (STAT6) and Signal transducer and activator of transcription 3 (STAT3), IL25 stimulation led to the activation of Signal transducer and activator of transcription 5A or 5B (STAT5), as indicated by the phosphorylation of STAT5 (Wu et al. 2015).
This is a black box event since the details about of the phosphorylated region could be incomplete.

Literature References
PubMed ID Title Journal Year
25821217 A novel IL-25 signaling pathway through STAT5 J. Immunol. 2015
External Reference Information
External Reference
Gene Names
STAT5A, STAT5
Chain
chain:1-794
Other Identifiers
0006130377
11717178_a_at
11745364_a_at
16834273
203010_at
27873
3721659
3721661
3721662
3721663
3721664
3721667
3721669
3721670
3721671
3721672
3721673
3721674
3721676
3721678
3721680
3721681
3721683
3721684
3721685
3721687
3721688
3721689
3721690
3757791
3757799
3757800
3757801
3757807
3860
40458_at
42128
49883
506_s_at
51156
6776
75183_at
8007212
A_14_P103776
A_14_P118146
A_23_P207367
A_24_P173088
AAA73962
AAB06589
AAH27036
ABF17939
BAH13486
CAB003860
CCDS11424
CCDS74067
ENSG00000126561
ENSP00000341208
ENSP00000443107
ENSP00000468749
ENST00000345506
ENST00000546010
ENST00000590949
EntrezGene:6776
g4507256_3p_at
GE81241
GO:0000255
GO:0001938
GO:0003677
GO:0003700
GO:0004713
GO:0004871
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006101
GO:0006103
GO:0006105
GO:0006107
GO:0006351
GO:0006355
GO:0006357
GO:0006549
GO:0006573
GO:0006600
GO:0006631
GO:0007165
GO:0007259
GO:0007595
GO:0018108
GO:0019530
GO:0035723
GO:0038111
GO:0040014
GO:0043536
GO:0046449
GO:0060397
HGNC:11366
HPA027873
HPA042128
HPA049883
HPA051156
Hs.437058
ILMN_1753547
MIM:601511
NM_001288718
NM_001288719
NM_003152
NP_001275647
NP_001275648
NP_003143
PF00017
PF01017
PF02864
PF02865
PH_hs_0025570
SM00252
SM00964
STAT5A
STAT5A-201
STAT5A-207
STAT5A-211
TC17000523.hg
U43185_s_at
uc002hzj.3
uc010cya.3
uc010cyc.3
UPI0000136075
UPI0000D6F8A8
XM_005257624
XP_005257681
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
ZINC - Substances
GeneCards
ZINC target
PRO
ZINC - Predictions - Purchasable
Interactors (6)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P18031 PTPN1  1 0.558 2
 UniProt:Q9UGK3 STAP2  2 0.556 11
 UniProt:P03372 ESR1  3 0.524 2
 UniProt:P00533 EGFR  58 0.508 3
 UniProt:P22681 CBL  7 0.488 2
 UniProt:P46109 CRKL  2 0.462 2