Reactome | CCNA2 gene expression is inhibited by RBL1 and RBL2

CCNA2 gene expression is inhibited by RBL1 and RBL2

Stable Identifier

R-HSA-8964588

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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CCNA2 gene expression is inhibited by RBL1 and RBL2

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In G0 and early G1, complexes containing p130 (RBL2) and p107 (RBL1), respectively, and histone deacetylase HDAC1 bind the promoter of the CCNA2 gene (Rayman et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
11959842	E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex Catchpole, S, Dynlacht, BD, te Riele, H, Dannenberg, JH, Watson, RJ, Rayman, JB, Indjeian, VB, Takahashi, Y	Genes Dev	2002