TOP2A gene gene expression is repressed by the DREAM complex

Stable Identifier
R-HSA-8964531
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
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TOP2A gene gene expression is repressed by the DREAM complex
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The DREAM complex directly represses the TOP2A gene transcription (Litovchick et al. 2007).

Literature References
PubMed ID Title Journal Year
17531812 Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence

Litovchick, L, Sadasivam, S, Florens, LA, Zhu, X, Swanson, SK, Velmurugan, S, Chen, R, Washburn, MP, Liu, XS, DeCaprio, JA

Mol Cell 2007
Participants
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Output
Participant Of
hasEvent
This event is regulated
Negatively by
Authored
Orlic-Milacic, M  (2011-06-14)
Reviewed
MacPherson, D  (2011-08-25)
Created
Orlic-Milacic, M  (2017-02-17)