Chylomicron remodeling

Stable Identifier
R-HSA-8963901
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Chylomicron remodeling
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As chylomicrons circulate in the body, they acquire molecules of apolipoproteins C and E, and through interaction with endothelial lipases can lose a large fraction of their triacylglycerol. These changes convert them to chylomicron remnants which bind to LDL receptors, primarily on the surfaces of liver cells, clearing them from the circulation. This whole sequence of events is rapid: the normal lifespan of a chylomicron is 30 - 60 minutes (Redgrave 2004).
Literature References
PubMed ID Title Journal Year
14748717 Chylomicron metabolism

Redgrave, TG

Biochem. Soc. Trans. 2004
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Event Information
Go Biological Process
chylomicron remodeling (0034371)
Orthologous Events
Chylomicron remodeling (Bos taurus)
Chylomicron remodeling (Canis familiaris)
Chylomicron remodeling (Mus musculus)
Chylomicron remodeling (Rattus norvegicus)
Chylomicron remodeling (Sus scrofa)
Cross References
BioModels Database
Authored
D'Eustachio, P  (2007-04-30)
Reviewed
Jassal, B  (2016-01-27)
Created
D'Eustachio, P  (2017-02-14)
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