Intestinal lipid absorption

Stable Identifier
R-HSA-8963678
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Pathway
Species
Homo sapiens
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Niemann-Pick C1 Like 1 (NPC1L1) protein in enterocytes is critical for intestinal cholesterol and phytosterol absorption, and is the target of the drug ezetimibe (Davis et al. 2004).

Literature References
PubMed ID Title Journal Year
15173162 Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis

Davis, HR, Zhu, LJ, Hoos, LM, Tetzloff, G, Maguire, M, Liu, J, Yao, X, Iyer, SP, Lam, MH, Lund, EG, Detmers, PA, Graziano, MP, Altmann, SW

J. Biol. Chem. 2004
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