TK1 gene expression is stimulated by E2F1

Stable Identifier
R-HSA-8962039
Type
Reaction [omitted]
Species
Homo sapiens
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E2F1 directly stimulates transcription of the TK1 gene, encoding thymidine kinase (Dou et al. 1994, DeGregori et al. 1995, Giangrande et al. 2004).

Literature References
PubMed ID Title Journal Year
7623816 Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

DeGregori, J, Kowalik, T, Nevins, JR

Mol Cell Biol 1995
15014447 Combinatorial gene control involving E2F and E Box family members

Giangrande, PH, Zhu, W, Rempel, RE, Laakso, N, Nevins, JR

EMBO J. 2004
8288595 G1/S-regulated E2F-containing protein complexes bind to the mouse thymidine kinase gene promoter

Dou, QP, Zhao, S, Levin, AH, Wang, J, Helin, K, Pardee, AB

J. Biol. Chem. 1994
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